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Analytical Testing and Analysis of Residual Solvents

Residual Solvents are Chemicals and solvents used in the extraction process and are notorious for their carcinogenic properties, therefore it is important to know how much of these chemicals and solvents still remain in the products once the extraction process is complete. They can be tested as individual components or as a finished product. Residual Solvents are organic volatile chemicals and are separated into three classes: Class 1 residual solvents are highly toxic. Class 2 residual solvents are considered moderately toxic and Class 3 residual solvents are the least toxic. To determine the quality and safety levels of the chemicals used in production of cannabis concentrates. HS-GC-MS method is used to analyze cannabis products to determine what trace residues are present.



Raw Materials

Dried Plant Material

Oil, Tinctures

Creams, Lotions, Balms

Food supplements



Determination of Residual solvents designed for Cannabinoid products (20 compounds) using USP limits in various matrices by HS-GC-MS or;

Determination of Residual solvents (up to 54 compounds) using USP limits in various matrices by HS-GC-MS



10ml / 10g

Residual Solvent or processing Chemical CAS No.
1,2-Dichloroethane 107-06-2
Benzene 71-43-2
Chloroform 67-66-3
Ethylene oxide 75-21-8
Category II Residual Solvent or Processing Chemical CAS No. Action Level (μg/g)
Inhalable Cannabis and Cannabis Products Other Cannabis and Cannabis Products
Acetone 67-64-1 3100 5000
Acetonitrile 75-05-8 6 410
Butane 106-97-8 5000 5000
Ethanol 64-17-5 5000 5000
Ethyl acetate 141-78-6 5000 5000
Ethyl ether 60-29-7 5000 5000
Heptane 142-82-5 5000 5000
Hexane 110-54-3 70 290
Isopropyl alcohol 67-63-0 320 5000
Methanol 67-56-1 400 3000
Pentane 109-66-0 5000 5000
Propane 74-98-6 5000 5000
Toluene 108-88-3 30 890
Total xylenes (ortho-, meta-, para-) 1330-20-7 10 2170

Types of Analytical Testing